Clinical trials & drug development MCP servers

A server here clinical trials, drug discovery or drug and device regulation.

Not here: medications for patients.

112servers
82 remote30 localTagged by Odel's AI, which can make mistakes
By GitHub stars, at most two per publisher
  1. Number 1: ToolUniverse@mims-harvard/tooluniverse2,700+ scientific tools for AI scientists: life science, research, literature, and more.4% chance this is malicious. Assessed by AI, which can make mistakes.Runs on your machine, installed from PyPI.1,718 GitHub stars.
  2. Number 2: clinicaltrialsgov-mcp-server@cyanheads/clinicaltrialsgov-mcp-serverSearch ClinicalTrials.gov — find studies, retrieve results, match patients to eligible trials.2% chance this is malicious. Assessed by AI, which can make mistakes.A remote server; no sign-in.97 GitHub stars.
  3. Number 3: Opentargets@nickzren/opentargetsRead-only Open Targets: targets, diseases, drugs and evidence by name or ID. No API key needed.3% chance this is malicious. Assessed by AI, which can make mistakes.Runs on your machine, installed from PyPI.19 GitHub stars.

Best fit

68 made for this, ranked by starsRemoteLocal
  1. BioMCP-TS @yeyuan98/biomcp-tsBiomedical MCP server: genes, variants, trials, literature, patents, optional SQL/R/biowasm tools.4% chance this is malicious. Assessed by AI, which can make mistakes.Runs on your machine, installed from npm.12 GitHub stars.
  2. Biopharma Catalyst @yesc97/biopharma-catalyst-mcpForensic biopharma catalyst auditor — 10 tools, deterministic CLEAN/BEAR_SIGNAL verdict.9% chance this is malicious. Assessed by AI, which can make mistakes.Runs on your machine, installed from npm.5 GitHub stars.
  3. AlphaFold Sovereign MCP @smaniches/alphafold-sovereign-mcpMCP server for AlphaFold and 8 other biomedical data sources with a local SQLite knowledge graph5% chance this is malicious. Assessed by AI, which can make mistakes.Runs on your machine, installed from PyPI.4 GitHub stars.
  4. UniProt MCP @smaniches/uniprot-mcpVerifiable, release-aware protein evidence workflows over UniProt and linked scientific sources.3% chance this is malicious. Assessed by AI, which can make mistakes.Runs on your machine, installed from PyPI.3 GitHub stars.
  5. Aria @pkotecha-eng/aria-mcp-serverSearch 35M+ PubMed, 400K+ ClinicalTrials.gov & ISRCTN trials. Prompts included. No API key.7% chance this is malicious. Assessed by AI, which can make mistakes.Runs on your machine, installed from PyPI.3 GitHub stars.
  6. Clinical Trial Design @wei-ai-lab/clinical-trial-designPhase 2/3 clinical trial design via gsDesign / gsDesign2: sample size, GS boundaries, multiplicity3% chance this is malicious. Assessed by AI, which can make mistakes.Runs on your machine, installed from npm.2 GitHub stars.
  7. cmxflow @b-shields/cmxflowComposable, tunable cheminformatics workflows: library preparation, clustering, docking, and more.3% chance this is malicious. Assessed by AI, which can make mistakes.Runs on your machine, installed from PyPI.2 GitHub stars.
  8. GWAS Bioinformatics MCP Server @zaeyasa/gwas-mcpAccess 30+ bioinformatics tools from 14 databases.4% chance this is malicious. Assessed by AI, which can make mistakes.Runs on your machine, installed from PyPI.1 GitHub stars.
  9. Amass @amass/amassLinked life-science search: 43M+ papers, 1.2M+ trials, drugs, genes, FDA/EMA approvals, patents.7% chance this is malicious. Assessed by AI, which can make mistakes.A remote server; you sign in with your account.1 GitHub stars.
  10. chembl-mcp-server @cyanheads/chembl-mcp-serverLink compounds to protein targets, rank bioactivity, and look up drug mechanisms and indications.2% chance this is malicious. Assessed by AI, which can make mistakes.A remote server; no sign-in.1 GitHub stars.
  11. FDA Approvals @guptaprakhariitr/fda-approvals-mcpFDA drug approvals, 510(k) device clearances, recalls and adverse-event reports.9% chance this is malicious. Assessed by AI, which can make mistakes.A remote server; no sign-in.1 GitHub stars.
  12. Anzctr @pipeworx-io/anzctrANZCTR — the Australian New Zealand Clinical Trials RegistryNot assessed yet.A remote server; no sign-in.
  13. BioAI 日知 @minsyang/bioai-rizhiRead-only AI biopharma news, research records, companies, and source status from BioAI 日知.4% chance this is malicious. Assessed by AI, which can make mistakes.A remote server; no sign-in.
  14. DrugAlpha 创新药投研 @max-nobug/drugalpha-mcpCompany/drug identification and published biopharma catalysts. DrugAlpha OAuth account required.Not assessed yet.A remote server; you sign in with your account.
  15. Agentic Target Evidence @athril/agentic-target-evidenceRead-only biomedical evidence tools for drug-target validation: DepMap, gnomAD, OpenTargets, PubMed…3% chance this is malicious. Assessed by AI, which can make mistakes.Runs on your machine, installed from Docker.
  16. Dog Geroscience @w0lph/dog-geroscience-mcpDog-specific aging tools: HAGR dog rows, dog orthologs, dose translation, DAP codebooks, FDA FOI.Not assessed yet.Runs on your machine, installed from PyPI.
  17. ClinicalTrials.gov MCP by usefulapi @usefulapi/clinicaltrialsgovSearch and read ClinicalTrials.gov studies, sites and outcomes.Not assessed yet.A remote server; no sign-in.
  18. Opentargets @mrfentmen/opentargets-mcpKeyless MCP server for Open Targets: gene/disease/drug search, target details, disease associations.5% chance this is malicious. Assessed by AI, which can make mistakes.Runs on your machine, installed from npm.
  19. ClinicalTrials @mrfentmen/clinicaltrials-mcpClinicalTrials.gov search and PubMed.5% chance this is malicious. Assessed by AI, which can make mistakes.Runs on your machine, installed from npm.
  20. Bindingdb @pipeworx-io/bindingdbBindingDB — measured protein/small-molecule binding affinities.5% chance this is malicious. Assessed by AI, which can make mistakes.A remote server; no sign-in.
  21. Biolab MCP Server @srikarjy/biolab-mcp-serverAuditable MCP server for PubMed, Europe PMC, ClinicalTrials.gov, and bioRxiv/medRxiv queries6% chance this is malicious. Assessed by AI, which can make mistakes.A remote server; no sign-in.

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