Scientific computing MCP servers

A server here theorem proving, symbolic maths, physics or engineering simulation.

Not here: business or finance calculators, trading backtests and simple arithmetic.

417servers
162 remote255 localTagged by Odel's AI, which can make mistakes

Best fit

280 made for this, ranked by starsRemoteLocal
  1. Rosetta @arielbs/rosetta-mcp-serverRosetta/PyRosetta protein modeling and Biotite translation for computational biology3% chance this is malicious. Assessed by AI, which can make mistakes.Runs on your machine, installed from npm.19 GitHub stars.
  2. Sidereon @neilberkman/sidereonGNSS positioning and astrodynamics: orbit propagation, passes, GNSS solves, and RINEX QC4% chance this is malicious. Assessed by AI, which can make mistakes.Runs on your machine, installed from MCPB.18 GitHub stars.
  3. ChemDraw MCP (unofficial) @jurimaxam-dotcom/chemdraw-mcpMolecule names or SMILES to 2D structures, reactions, mechanisms, spectra - offline via RDKit.6% chance this is malicious. Assessed by AI, which can make mistakes.Runs on your machine, installed from PyPI.18 GitHub stars.
  4. Mass Spectrometry Data (mzML, Bruker TDF, vendor conversion) @k-dense-ai/labmcp-ms-dataMCP server for LC-MS data in mzML/mzMLb and Bruker timsTOF files; vendor formats via msconvert.3% chance this is malicious. Assessed by AI, which can make mistakes.Runs on your machine, installed from PyPI.17 GitHub stars.
  5. Dense Evolution @tatopenn-cell/dense-evolutionReal quantum circuit simulator, VQE, molecular Hamiltonians, QM/MM forces, and MD via 21 tools.4% chance this is malicious. Assessed by AI, which can make mistakes.Runs on your machine, installed from PyPI.17 GitHub stars.
  6. SageMath @xbp-europe/sagemath-mcpStateful SageMath MCP server with 40 tools and a sandboxed Sage session per client.3% chance this is malicious. Assessed by AI, which can make mistakes.Runs on your machine, installed from PyPI.16 GitHub stars.
  7. Mathlas @archerkattri/mathlasAirtight math for AI agents: 3.68M-doc theorem search + numeric/Lean verification. No LLM, no key.3% chance this is malicious. Assessed by AI, which can make mistakes.Runs on your machine, installed from PyPI.13 GitHub stars.
  8. Prolog Reasoner @rikarazome/prolog-reasonerSWI-Prolog as a logic calculator for LLMs3% chance this is malicious. Assessed by AI, which can make mistakes.Runs on your machine, installed from PyPI.12 GitHub stars.
  9. AgentSUMO @mw-jeong/agentsumo-mcpMCP server for LLM-driven SUMO traffic simulation, scenario design, and result analysis.3% chance this is malicious. Assessed by AI, which can make mistakes.Runs on your machine, installed from PyPI.11 GitHub stars.
  10. SCHISM Model Setup MCP Server @oceanmodeling/schism-mcpSCHISM model configuration debugging, parameter lookup, and validationNot assessed yet.Runs on your machine, installed from PyPI.9 GitHub stars.
  11. ADCIRC Model Setup MCP Server @oceanmodeling/adcirc-mcpADCIRC model configuration debugging, parameter lookup, and validationNot assessed yet.Runs on your machine, installed from PyPI.9 GitHub stars.
  12. VDatum MCP Server @mansurjisan/vdatum-mcpMCP server for vertical datum conversions using coastalmodeling-vdatum4% chance this is malicious. Assessed by AI, which can make mistakes.Runs on your machine, installed from PyPI.9 GitHub stars.
  13. AnkusDrive @gchen19/ankusdriveDrive FreeCAD from an agent: CAD modeling, drawings, FEM, CFD, EM, and multiphysics simulation.5% chance this is malicious. Assessed by AI, which can make mistakes.Runs on your machine, installed from PyPI.9 GitHub stars.
  14. Colab Exec @pdwi2020/mcp-server-colab-execExecute Python code on Google Colab GPU runtimes (T4/L4) from any MCP client9% chance this is malicious. Assessed by AI, which can make mistakes.Runs on your machine, installed from PyPI.9 GitHub stars.
  15. Sounio Compiler @agourakis82/sounio-mcp-serverCheck, compile, run, and test Sounio programs locally.3% chance this is malicious. Assessed by AI, which can make mistakes.Runs on your machine, installed from PyPI.9 GitHub stars.
  16. Motor Current Signature Analysis @lgdimaggio/mcp-server-mcsaMCP server for Motor Current Signature Analysis — fault detection in electric motors3% chance this is malicious. Assessed by AI, which can make mistakes.Runs on your machine, installed from PyPI.9 GitHub stars.
  17. MNE-MCP @exekiel179/mne-mcpMNE-Python neurophysiology analysis (EEG, MEG, sEEG, ECoG, fNIRS) via the Model Context Protocol4% chance this is malicious. Assessed by AI, which can make mistakes.Runs on your machine, installed from PyPI.9 GitHub stars.
  18. Endiagram @dushyant30suthar/endiagram-mcpEN Diagram — structural verification for concurrent systems. Pure math, no AI.7% chance this is malicious. Assessed by AI, which can make mistakes.A remote server; no sign-in.8 GitHub stars.
  19. genpark-jitter-buffer @alpha-park/genpark-jitter-bufferPacket ordering simulation and inter-arrival jitter telemetry.3% chance this is malicious. Assessed by AI, which can make mistakes.Runs on your machine, installed from MCPB.7 GitHub stars.
  20. Mathematica @lars20070/mathematica-mcpMCP server for WolframScript5% chance this is malicious. Assessed by AI, which can make mistakes.Runs on your machine, installed from PyPI.7 GitHub stars.
  21. Rftools @antonpogrebenko-public/rftools255 RF & electronics calculators + 13 simulation tools for AI agents.3% chance this is malicious. Assessed by AI, which can make mistakes.Runs on your machine, installed from npm.7 GitHub stars.
  22. PLAXIS @yixuanzhong/plaxis-mcpWindows-local MCP server for PLAXIS 2D Remote Scripting: geometry, staged construction, results.4% chance this is malicious. Assessed by AI, which can make mistakes.Runs on your machine, installed from PyPI.6 GitHub stars.
  23. OpenHCS @openhcsdev/openhcsInspect, author, validate, and run high-content microscopy workflows.2% chance this is malicious. Assessed by AI, which can make mistakes.Runs on your machine, installed from PyPI.6 GitHub stars.
  24. Kshana PNT-resilience simulator @ashfordeou/kshana-mcpRun the validated Kshana PNT-resilience simulator (orbits, frames, GNSS, fusion) from an AI agent.2% chance this is malicious. Assessed by AI, which can make mistakes.Runs on your machine, installed from Docker.6 GitHub stars.